Overview of Frontline2

The understanding of best practice for preventing and treating thrombosis in cancer patients has evolved since the first Frontline survey in 2001, but contemporary evidence suggests that variations in practice still persist.[1],[2]

Frontline2 is a cancer associated thrombosis (CAT) survey of oncologists, haematologists, surgeons, thrombosis specialists, members of the palliative care team and specialist nurses to identify the factors and evidence that now inform the decisions made by those responsible for treating CAT. This will provide an opportunity to describe the evolution of clinical understanding in this area since 2001, and the rationale behind variations in care, nationally and internationally, in 2016.

Key survey objectives will be the assessment of:

  • The awareness of current guidelines for the management of CAT
  • The use of anticoagulants for the acute management of CAT
    • Patient types and characteristics
    • Preferred treatment agents
    • Duration of therapy
  • The use of and extended treatment duration (greater than 6 months) for prevention of subsequent CAT
    • Patient types and characteristics
    • Preferred treatment agents
  • The use of thromboprophylaxis in patients receiving active chemotherapy

[1] Kakkar AK, Levine M, Pinedo HM, Wolff R, Wong J. Venous thrombosis in cancer patients: insights from the FRONTLINE survey. Oncologist. 2003;8(4):381-8. To view the full Frontline1 paper click here [2] Amin A, Stemkowski S, Lin J, Yang G. Appropriate thromboprophylaxis in hospitalized cancer patients. Clin Adv Hematol Oncol. 2008;6(12):910-20.

Once you have completed the survey please do not forget to collect your honorarium in addition to the Free Cancer Associated Thrombosis Educational Material we have prepared for you as a thank you for your time and participation! This can be found in the ‘Free Educational Materials’ section.

 

Steering Committee

A Scientific steering committee will oversee the design and implementation of the study, alongside independent audit and publication committees.

Steering Committee members

Professor Lord AJay Kakkar (UK), chair
Professor Mark Levine (Canada)
Professor Anna Falanga (Italy)
Professor John Wong (Singapore)
Professor Rupert Bauersachs (Germany)
Dr. Rodney Hughes (UK)


The Frontline2 Survey is funded by an unrestricted research grant from Bayer Pharma AG